SEND Explorer® is a validated, web-based application designed by scientists to provide advanced viewing, data summarization, and visualization capabilities for nonclinical study data. SEND Explorer can consume data in SEND 3.0/3.1/3.1.1 format, in a variety of non-SEND data formats (including interim study formats), and via direct connection to a data collection system. SEND Explorer empowers scientists to interact with their study data, visualize treatment and/or time-related patterns, and communicate relationships with other scientists. SEND Explorer allows organizations to leverage their investment in creating SEND datasets for regulatory submissions, by making study data and associated visualizations readily accessible to scientists for internal decision-making.
Our latest release, v11, includes even more visualizations and customization options, adding scientific value and enhanced usability! To learn more about all the new features and enhancements in SEND Explorer v11, read the full announcement linked below.
Volumes of Data? Empower your scientists!
Visualize patterns and trends over time
SEND Explorer provides an “easy-button” which scientists can use to generate single-study plots from nonclinical study data to reveal dose-response and timecourse patterns including:
- Summary View for Numeric Data to visualize patterns and trends in numeric data with summary statistics, scatterplot, out-of-concurrent-control range indicator, and % control mean calculations
- Summary View thumbnail plots to display distribution of subject data across groups
- Line Graphs to visualize patterns of group means and individual subject data over time
- Clinical Observations Timecourse to reveal dose-related patterns and trends in clinical observations over the course of a study
- Severity Heatmap to visualize patterns and trends in both incidence and severity of pathology findings
- Cross-Domain Subject View to put a subject’s data into perspective as compared to its own group and control group, on a single day or over time
- Single-Study Survival Plot to plot survival in long-term studies
Gain insights from multi-study visualizations
SEND Explorer provides powerful yet intuitive cross-study querying capabilities and multi-study visualizations.
- Correlations Matrix to reveal pairwise correlations of endpoints for selected subjects, identifying those with histopathology findings in tissues of interest
- Multi-Study Scatterplot Timecourse to compare and contrast dose-response and timecourse relationships in a selected endpoint for a group of related studies with the ability to overlay historical control reference range values
- Multi-Study Histopathology Barchart to visualize prevalence and severity of histopathology findings across studies or in untreated control subjects
- Historical Control Distribution to reveal the distribution of numeric data in control subjects across studies, stratified by selected fields of interest
- Multi-Study Line Graph to compare study-specific timecourse patterns in group means and individual subject data for one or more selected endpoints across studies
Choose the SEND Explorer option that fits your exact needs
There are 3 different options for SEND Explorer software.
SEND Explorer: Single-study functionality, ability to review and query SEND data, generate visualizations to identify trends; and review all data for a single subject to identify patterns across endpoints of interest, at a given time point and over time
SEND Explorer Plus: Additionally includes a SEND-optimized database to extend functionality to the multi-study environment for SEND 3.x XPT datasets and provides powerful yet intuitive cross-study querying capabilities and multi-study visualizations
SEND Explorer Warehouse: Supports a variety of source data formats including direct connection to data collection systems, and additionally handles custom domains and provides term reconciliation functionality, record override and the ability to create and populate ad hoc study metadata fields for querying data and filtering visualizations
Certara also offers toxicology, nonclinical, and other IND-enabling support with our drug development consultancy to help you reach your goals. Contact us to learn how our tools and quantitative approaches have helped thousands of clients.
Having worked in the Pharmaceutical industry her entire career, Joyce has developed a passion for partnering with scientists to design tools which allow them to interact with their study data, to visualize patterns and trends, and to communicate relationships with other scientists. She has been thrilled to see SEND Explorer help organizations embrace a culture of analytic excellence and data-informed decision-making, putting the right tools in the hands of bench scientists and drug development team leaders alike.
Peggy is the Customer Success lead for SEND Explorer. She has a strong background in nonclinical data management, warehousing and the SEND standard, including serving as the lead of the CDISC SEND controlled terminology team for over 7 years. She continues to be involved in the CDISC SEND team as well as the PhUSE nonclinical working group.
Prior to joining Certara, Peggy worked for 15 years at Pfizer, with 6 of those years focused on nonclinical data management and warehousing. She also worked for INDS for several years, which is the company that originally developed the SEND Explorer dataset reviewer and visualization tool.
Having worked in the Pharmaceutical industry her entire career, Joyce has developed a passion for partnering with scientists to design tools which allow them to interact with their study data, to visualize patterns and trends, and to communicate relationships with other scientists. She has been thrilled to see SEND Explorer help organizations embrace a culture of analytic excellence and data-informed decision-making, putting the right tools in the hands of bench scientists and drug development team leaders alike.
Peggy is the Customer Success lead for SEND Explorer. She has a strong background in nonclinical data management, warehousing and the SEND standard, including serving as the lead of the CDISC SEND controlled terminology team for over 7 years. She continues to be involved in the CDISC SEND team as well as the PhUSE nonclinical working group.
Prior to joining Certara, Peggy worked for 15 years at Pfizer, with 6 of those years focused on nonclinical data management and warehousing. She also worked for INDS for several years, which is the company that originally developed the SEND Explorer dataset reviewer and visualization tool.